Sialic acid acetylesterase
WebMay 25, 2024 · Using reverse transcription-polymerase chain reaction to distinguish the two forms of message, we show that although the lysosomal sialic acid-specific 9-O-acetylesterase message has a widespread ... Web(Click on the icon in the table below to see search hit context)
Sialic acid acetylesterase
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WebJun 19, 2024 · Sialic acids are nine-carbon sugars that frequently cap glycans at the cell surface in cells of vertebrates as well as cells of certain types of invertebrates and … WebDocument: Group 2 coronaviruses encode an accessory envelope glycoprotein species, the hemagglutinin esterase (HE), which possesses sialate-O-acetylesterase activity and …
The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction ... "High performance liquid chromatography of enzymes of sialic acid metabolism". Hoppe-Seyler's Z. Physiol. Chem. 363: 1039–1040. This page was last edited on 16 August 2024, at 15:45 (UTC). Text is available under the Creative … See more The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate In human it is encoded by the SIAE gene located on See more The SIAE gene contains 15 exons and expresses a protein that is approximately 56 kDa in size. It is known to be expressed in the adult See more SIAE activity negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of immunological tolerance. It down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for See more Genetic defects in SIAE have been associated with multiple autoimmune diseases. Loss of function mutations in SIAE are much more frequently found in humans with See more WebAmong coronaviruses, several members are able to interact with sialic acids. For bovine coronavirus (BCoV) and related viruses, binding to cell surface components containing N-acetyl-9- O-acetylneuraminic acid is essential for initiation of an infection. These viruses resemble influenza C viruses because they share not only the receptor determinant, but …
WebJun 29, 2024 · Here, we focused on modulating 9-O and 7, 9-O-acetylation of Neu5Ac, via CRISPR-Cas9 gene editing, a functional group that is absent from Sias on many types of cancer cells. The two genes that are responsible for regulating the level of acetylation on Neu5Ac, are Sialic acid acetylesterase (SIAE) and Sialic acid acetyltransferase (CASD1). WebOct 20, 2014 · Nucleic Acids Research Sep 2012 ... Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic …
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WebAug 24, 2010 · Sialic acids are acidic 9-carbon sugars typically found at the nonreducing end of sugar chains. They are frequently modified by 9-O-acetylation, and this modification is … inclination\u0027s 45WebA sialic acid-specific O-acetylesterase in human erythrocytes: possible identity with esterase D, the genetic marker of retinoblastomas and Wilson disease. by A Varki, E Muchmore, S … inclination\u0027s 42WebSep 28, 2024 · SIAE sialic acid acetylesterase Gene ID: 54414, updated on 28-Sep-2024 Gene type: protein coding Also known as: ... This gene encodes an enzyme which … inclination\u0027s 48WebMar 21, 2024 · SIAE (Sialic Acid Acetylesterase) is a Protein Coding gene. Diseases associated with SIAE include Autoimmune Disease 6 and Autoimmune Disease. Gene … inbred chickenWebSialic Acid Acetylesterase is also known as H-Lse, SIAE, Sialate O-acetylesterase, Yolk sac protein 2, YSG2 . Open Advanced Filter 7 Applications, 4 Species currently selected. OR … inclination\u0027s 47WebMar 30, 2024 · These core structures are further elongated and frequently modified by fucose and sialic acid sugar residues via α1,2/3/4 and α2 ... Kriaris M. S., Hoskins L. C. … inclination\u0027s 46WebOct 1, 2024 · Sialic acid acetylesterase (SIAE) removes acetyl moieties from the carbon 9 and 4 hydroxyl groups of sialic acid and recently a debate has been opened on its … inclination\u0027s 4h