Malat1 endothelial

Author: jijo

August undefined, 2024

Web5 feb. 2024 · Long noncoding RNA MALAT1 promotes high glucose-induced inflammation and apoptosis of vascular endothelial cells by regulating miR-361-3p/SOCS3 axis. Kai Huang, Xuxia Yu, Yushan Yu, Lu Zhang, Y. Cen, Jinguo Chu Biology, Medicine International journal of clinical and experimental pathology 2024 TLDR WebLncRNA MALAT1 facilitates BM-MSCs differentiation into endothelial cells via targeting miR-206/VEGFA axis. Bone marrow-derived mesenchymal stem cells (BM-MSCs) implantation shows a repair effect on erectile function in diabetes mellitus-induced …

LncRNA MALAT1 up-regulates VEGF-A and ANGPT2 to

Web18 jan. 2024 · Findings from our in vitro experiments demonstrated that MALAT 1 was predominantly localized to nuclear speckles in endothelial cells and MALAT 1 expression was significantly increased following incubation with high glucose in association with increased expression of inflammatory cytokines. WebExosomal MALAT1 derived from oxidized low-density lipoprotein-treated endothelial cells promotes M2 macrophage polarization. Oxidized low-density lipoprotein (oxLDL)-induced injury and apoptosis of endothelial cells are important initial events in numerous … h-sil

(PDF) Knockdown of lncRNA MALAT1 Alleviates LPS-Induced …

Web5 feb. 2024 · Recently, MALAT1 was identified as a pyroptosis-related long noncoding RNA (lncRNA). Here, we investigated the potential role and underlying mechanism of lncRNA MALAT1 in endothelial cells pyroptosis. We first established an endothelial cell … Web8 feb. 2024 · lncRNA-MALAT1 promotes high glucose-induced H9C2 cardiomyocyte pyroptosis by downregulating miR-141-3p expression. ... Zörnig M, Braun T, John D, Ponomareva Y, Chen W, Uchida S, et al. Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth. Circ Res. 2014; 114:1389–1397. doi: … Web12 apr. 2024 · 国家自然基金委通报今年首批八起学术不端案件，七起涉“医”. 4月11日，国家自然科学基金委员会官网通报了2024年查处的不端行为案件第一批次8个案件的处理结果。. 因涉嫌买卖实验数据、伪造实验数据、擅自标注基金项目、未经同意使用他人署名、伪造他人 ... h-sun

Endothelial Cell Marker Antibody Duo (CD31, CD34) …

2024年查处的不端行为案件处理结果通报（第一批次）

WebMALAT1 is associated with vascular endothelial cell homeostasis , and reduced MALAT1 expression may impede vascular repair after SARS-CoV-2 infection. MT-CO1 (ENSG00000198804), as a second parameter, was downregulated in vascular … Webpaper showed that MALAT1 controls a phenotypic switch in endothelial cell and regulates its function and vessel growth [18]. It has also been demonstrated that MALAT1 plays a pathogenic role in endothelial cell dysfunction in diabetes mellitus [19]. However, whether MALAT1 is in-volved in regulating EPC function in T2DM remains un-known. autorisation velux voisinWeb6 mrt. 2024 · The present study aimed to investigate the functional roles of MALAT1 in regulating miR-145 and its downstream pro-angiogenesis factors, vascular endothelial growth factor (VEGF)-A and Angiopoietin-2 (ANGPT2) during the progress of … h-sushi bastia pd

"Web6 apr. 2024 · Besides, Malat1 is involved in pathogenesis of various vascular diseases by regulating endothelial, smooth muscle cell and hematopoietic stem cell functions [22,23,24]. Cremer et al . found that suppressed Malat1 level augments atherosclerotic lesion formation in mice and that Malat1 inhibits Lin − Sca1 + c-kit + (LSK) progenitor cell proliferation [ 24 ]. " - Malat1 endothelial

Malat1 endothelial

WebMALAT1 modulated MEF2A expression positively by sponging miR-181b-5p. Conclusions: Endothelial function is reduced in CSF. MALAT1 participates in regulating CSF endothelial dysfunction through the miR-181b-5p-MEF2A-ET-1 axis, and could provide a new target … WebZhu, Y., Yang, T., Duan, J., Mu, N., & Zhang, T. (2024). MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic ...

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WebMalignant endothelial cells also commonly retain the antigen, so that CD31 immunohistochemistry can also be used to demonstrate both angiomas and angiosarcomas. ARG30300 Endothelial Cell Marker Duos, including antibodies react commonly used endothelial cell marker CD31 and CD34 for angiogenesis study. Endothelial Cell … Web15 feb. 2024 · However, the function of Malat1 in the cerebral vasculature after stroke has not been studied. Our previous study using RNA-sequencing (RNA-seq) technology has identified Malat1 as one of the most highly upregulated oxygen-glucose deprivation (OGD)-responsive endothelial lncRNAs ( Zhang et al., 2016 ).

Web26 jun. 2024 · Ischemic stroke (IS) is a common disease that seriously endangers human health. Patients with IS present with increased death of brain microvascular endothelial cells (BMECs). MALAT1 is found to be upregulated in IS patients. However, the function of MALAT1 in IS pathogenesis still remains unclear. Web25 mei 2024 · 文献：Single-cell RNA sequencing reveals the sustained immune cell dysfunction in the pathogenesis of sepsis secondary to bacterial pneumonia. 先分大群. T/NK cells (CD3D+ IL32+ NKG7+), myeloid cells (CD14+ FCGR3A+ S100A9+) and B cells (CD79B+ CD79A+ IGHM+) 再细分亚群. 禁止转载，如需转载请通过简信或评论联系作者。.

Web30 okt. 2014 · MALAT1 knockdown could obviously ameliorate DR in vivo, as shown by pericyte loss, capillary degeneration, microvascular leakage, and retinal inflammation. Moreover, MALAT1 knockdown could regulate retinal endothelial cell proliferation, … Web19 mrt. 2015 · MALAT1 (AKA NEAT2: noncoding nuclear-enriched abundant transcript 2, HCN, LINC000 47) is a large, infrequently spliced non-coding RNA, which is highly conserved. MALAT1 is expressed in the nucleus and was originally described to regulate …

Web21 feb. 2024 · Objective: Present study focused on the influence of lncRNA MALAT1 on coronary atherosclerotic heart disease (CAD) by regulating miR-15b-5p/MAPK1 and mTOR signaling pathway.Method: Differentially expressed genes and activated pathway were …

Web25 apr. 2024 · Here, we first determined the expression level of MALAT1 in human retinal microvascular endothelial cells (HRECs) cultured in high glucose (HG) and subsequently analyzed the expressions of... autorisation vaudWeb18 jun. 2024 · MALAT1 and MIAT lncRNAs are associated with the angiogenesis process. MALAT1 induces hypoxia-driven angiogenesis via the overexpression of angiogenic genes. Down regulation of MIAT1 could inhibit the proliferation of … autoriseren synoniemWeb10 sep. 2024 · Background . Endothelial dysfunction commonly occurs in obese children and adolescents, leading to an increased risk of cardiovascular diseases. Exercise has significant protective effects against endothelial dysfunction through regulating some noncoding RNAs. This study aimed to investigate the relationship of long noncoding RNA … autoriser synonymeWeb6 okt. 2024 · MALAT1 knockdown significantly improved viability and suppressed the apoptosis of LPS-stimulated HPAEpiC. Moreover, MALAT1 directly targeted miR-194-5p, ... in VILI yet. Methods: To screen the differential expression of lncRNAs and mRNAs in Human pulmonary microvascular endothelial cells (HPMECs) subjected to cyclic stretch, ... autorisation veranda voisinWeb13 jan. 2024 · MALAT1 knockdown increased the level of miR-19b-3p in cells, and increased miR-19b-3p further inhibited the expression of HIF-1α, thereby reducing the HYP-induced HUVECs apoptosis, autophagy and inflammation. Taken together, these results suggest that MALAT1 may be a potential target for mitigating HYP-induced endothelial … autorisation visite hopitalWebA previous study indicated that metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) promotes neuronal death via targeting miR-30a in ischemic stroke. 49 It protects the cerebral microvasculature and parenchyma from cerebral ischemic insults by inhibiting endothelial cell death and inflammation and plays roles in the progression of ... autoriseminantiWebFor example, lncRNA MALAT1 can directly bind to miR-22–3p, resulting in increased expression of downstream target protein chemokine (C-X-C motif) receptor (CXCR) and activation of the downstream Akt pathway, thereby impairing endothelial cell function [88]. autorisert synonym