WebJun 1, 1996 · Myocardial matrix metalloproteinase(s): localization and activation. Mol Cell Biochem. 1993 Sep 8; 126 (1):49–59. [Google Scholar] Jones PA, Werb Z. Degradation of connective tissue matrices by macrophages. II. Influence of matrix composition on proteolysis of glycoproteins, elastin, and collagen by macrophages in culture. WebJun 9, 2024 · 3.2. Expression of Elafin in Colorectal Cancer Patients in Different Clinicopathological Features Compared with Nontumor Tissues. Based on a high …
The serine protease inhibitor elafin maintains normal …
WebDec 3, 2007 · Elafin is an endogenous serine protease inhibitor and is transcriptionally down-regulated in most tumor cell lines. In this study, we show that C/EBPβ is differentially expressed in normal versus tumor cell lines and normal adjacent versus tumor tissues obtained from breast cancer patients. WebElafin binds to elastic fibers by transglutaminase-mediated cross-linking and protects against proteolytic breakdown. Decreased degradation could contribute to accumulation of elastotic material in photodamaged skin. Elastase and its locally produced inhibitors play a role in actinic elastosis. twr services in dallas
Cross-Linking of Elafin/SKALP to Elastic Fibers in ... - ScienceDirect
WebDec 31, 2014 · Elafin was originally characterized as an endogenous inhibitor of the serine proteases neutrophil elastase (NE) and proteinase 3 (PR3) [ 1 ]. Notably, elafin has also demonstrated anti-inflammatory, immune modulatory, and anti-microbial properties, independent of its protease inhibitory activity [ 2 ]. WebJun 1, 2007 · The fibrillary basophilic material present in the upper dermis of photodamaged skin is largely composed of elastic material. It is unclear to what extent this accumulation is caused by increased synthesis of elastin or by breakdown of existing and nascent elastic fibers, or by a relative decrease of collagen (Lewis et al., 2004; Sellheyer, 2003). ... WebApr 7, 2014 · Elafin, a human protein, plays a key role against the inflammatory reaction typical of celiac disease (gluten intolerance), research has shown. The researchers have … tamaie athos