Cisplatin and ckd
WebJul 24, 2024 · Cinacalcet is a calcimimetic agent that works by stimulating the CaSR and thus decreasing PTH secretion. It is used in the treatment of both primary and secondary hyperparathyroidism. The resulting … WebApr 25, 2014 · Cisplatin and other platinum derivatives are the most widely used chemotherapeutic agents to treat solid tumors including ovarian, head and neck, and …
Cisplatin and ckd
Did you know?
WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in … WebMethod: Two years of cisplatin prescriptions were retrospectively compared to the 4 and 3 ranges estimated glomerular filtration rate (eGFR)-stratified dosing …
WebApr 15, 2024 · A 52-year-old man developed mucositis and weight loss during treatment with cisplatin for high-grade squamous cell carcinoma (SCC) of the left nasal cavity … National Center for Biotechnology Information
WebHypertension is a common result of CKD, and the mechanisms that produce hypertension in CKD include increased vascular volume, elevation of peripheral vascular resistance, decreased levels of renal vasodilator prostaglandins, and increased activity of the renin-angiotensin-aldosterone system. WebNephrotoxicity: cisplatin for injection can cause severe renal toxicity, including acute renal failure. Severe renal toxicities are dose-related and cumulative. Ensure adequate …
Webcisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths injectable...
WebSilymarin is also protective against several classes of nephrotoxic drugs, in particular cisplatin and Adriamycin®, two of the most potent chemotherapeutic drugs—but also two of the most damaging to the kidney owing to oxidative damage and severe inflammation. 39-41 Researchers around the world have found that silymarin and its components reduce … howard berner principiaWebJun 1, 2024 · Cisplatin (CP)-induced nephrotoxicity is widely accepted as a model for acute kidney injury (AKI). Although cisplatin-induced chronic kidney disease (CKD) in rodent … how many hungarians live outside hungaryWebApr 11, 2024 · The poster shows the final data from a phase 2 study evaluating the ability of the DRP ® companion diagnostic for cisplatin to prospectively identify patients with metastatic breast cancer that ... how many hungarians died in the uprising 1956WebThe U.S. Food and Drug Administration granted cisplatin approval in treating testicular and ovarian cancer in 1978 ( Basu and Krishnamurthy, 2010 ). Now, Cisplatin is still widely used to treat a variety of solid tumors including bladder cancer, head and neck cancer, esophageal cancer, and so on. howard berlin ophthalmologyWeb42%–100% of patients depending on total cisplatin dose and length of exposure. Hypomagnesemia and renal magnesium wasting may persist for up to 6 years after … howard bernard fosterWebMar 13, 2024 · Cisplatin (cis-diamminedichloroplatinum II, CDDP) is one of the most effective chemotherapeutic agents. However, its clinical use is limited due to the severe side effects, including nephrotoxicity and acute kidney injury (AKI) which develop due to renal accumulation and biotransformation of CDDP. howard berlin md hollywood flWebAbstract Acute kidney injury (AKI) is a common clinical problem, and patients who survive AKI have a high risk of chronic kidney disease (CKD). The mechanism of CKD post-AKI, characterized by progressive renal fibrosis, is still unclear. Maladaptive tubular epithelial cells (TECs) after AKI are considered a leading cause of renal fibrosis post-AKI. howard bernstein scholarship fund